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Axel Lets
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Survival World Dos.7z

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Once injected into an injured tissue, MSCs face a harsh environment, including ROS, ischemia and anoikis, which may further induce cell apoptosis. Various preconditioning strategies, such as incubation with cytokines or chemical compounds, improvement of culture condition, thermosensitive hydrogel and genetic modification, can improve the survival rate and paracrine ability of MSCs and help them migrate to the target tissue in vivo

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Full Text Available The present article is based on Western, Japanese and field-work materials of the author who describes the main stages of formation of the Indian entrepreneurial diaspora in Japan in the period from the late 19th century until the beginning of the World War II. Indian entrepreneurs, being the representatives of trade and usury communities, Sindhis and Parsis in particular, started to arrive here in 1870s under British protection. Their main occupation was the export of Japanese textile which was the main export item of Japan in the mentioned period. Indians maintained the export of the textile goods, silk and cotton, in different countries all over the world through their strong entrepreneurial networks. The majority of Indian firms in Japan were Sindhis firms, and Sindhis network was especially prominent. Indian firms especially prospered in 1920-1930s, when their share of Japanese textile export constituted about 70 %. Thanks to strong ethnic loyalties, Indians in Japan could not only prosper but also successfully adapt to closed Japanese society. The article considers the pattern of settlement of Indians in Japan, and emphasizes two stages of Indian community formation in the pre-War period. The first one lasted from 1870s till 1923 year, when the community was formed basically in Yokohama. And the second stage after Great Kanto Earthquake lasted from 1923 till 1939, when it was constituted mainly in Kobe, which in present days remains the centre of Indian entrepreneurial community in Japan.

Full Text Available Hideaki Katagiri,1 Masanori Taketsuna,2 Shinpei Kondo,3 Kenta Kajimoto,4 Etsuko Aoi,5 Yuka Tanji1 1Bio-Medicines, Medicines Development Unit Japan, Eli Lilly Japan K.K., Kobe, Japan; 2Statistical Sciences, Medicines Development Unit Japan, Eli Lilly Japan K.K., Kobe, Japan; 3Post Marketing Study Management, Medicines Development Unit Japan, Eli Lilly Japan K.K., Kobe, Japan; 4Scientific Communications, Medicines Development Unit Japan, Eli Lilly Japan K.K., Kobe, Japan; 5Global Patient Safety Japan, Quality and Patient Safety, Eli Lilly Japan K.K., Kobe, Japan Objective: To assess the effectiveness and safety of oral olanzapine treatment transitioned from rapid-acting intramuscular olanzapine (RAIM in patients with acute agitation associated with schizophrenia in a real-world clinical setting. Methods: The postmarketing surveillance study with a 3-day observational period after the last RAIM administration was conducted (original study. Following this, an extended study was added for patients who received oral olanzapine after RAIM administration during the original study period, in order to additionally observe them for 7 days after initial RAIM administration. Effectiveness and safety from initial RAIM administration were evaluated using the Positive and Negative Syndrome Scale-Excited Component score and treatment-emergent adverse events (TEAEs, respectively. Results: The effectiveness and safety analysis set included a total of 521 and 522 patients, respectively. A majority of patients received 10 mg of RAIM (475/522 patients, 9


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